Antibiotic Resistance Industry Overview
The global antibiotic resistance market size was valued at USD 7.81 billion in 2017 and is estimated to reach USD 12.07 billion by 2025, registering a CAGR of 5.6% during the forecast period.
High burden of antibiotic-resistant infections and emergence of multi-drug resistant pathogens have been augmenting the market. Pharmaceutical companies, such as GlaxoSmithKline, Johnson & Johnson, Novartis, and Sanofi, are at the forefront of the global pharmaceutical industry but are less actively involved in clinical development of antibiotics. Majority of large pharmaceutical companies find the market lucrative enough due to relatively slower growth in revenues for marketed drugs and lower return on investments. For instance, Novartis recently canceled all plans to continue with R&D for its antibacterial drugs.
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On the other hand, there are several biotech companies including Melinta Therapeutics, Achaogen, and Nabriva Therapeutics that have undertaken the challenge of developing therapies for antibiotic resistance. Involvement of international organizations serves as a catalyst in developed markets. Funding bodies such as BARDA are supporting biotech companies with financial support to complete early stage development of their novel therapies for antibiotic resistant infections.
Manufacturers seek the Qualified Infectious Disease Product (QIDP) designation, which expedites the clinical review process and extends exclusivity period for new generation antibiotics of strong therapeutic value. The QIDP designation was introduced under the Generating Antibiotic Incentives Now (GAIN) Act, passed in 2012 as an extension to the U.S. Food and Drug Administration Safety and Innovation Act. The legislation aims to promote the development of new therapies for growing burden and severity of antibiotic-resistant infections.
Antibiotic Resistance Market Segmentation
Based on the Disease Insights, the market is segmented into cUTI, cIAI, BSI, CDI, ABSSSI, HABP/VABP and CABP
Based on the Pathogen Insights, the market is segmented into acinetobacter baumannii, pseudomonas aeruginosa, staphylococcus aureus, e. coli/k. pneumoniae, streptococcus pneumoniae, clostridium difficile, enterococcus faecium and haemophilus influenzae
Based on Drugs Class Insights, the market is segmented into oxazolidinones, lipoglycopeptides, tetracyclines, cephalosporins, combination therapies and others
Based on the Regional Insights, the market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa
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Market Share Insights:
Key Companies Profile:
Large pharmaceutical companies are acquiring smaller entrants with novel antibiotics. The trend is expected to shape the future of the market. For instance, Pfizer acquired Astra Zeneca’s marketed drugs, Zavicefta and Zinforo, and late stage antibiotics, ATM-AVI, resulting in an expanded portfolio of antibiotics. In addition, companies in the market target for higher market share through indication extension and geographic expansion strategies.
Some prominent players in the global antibiotic resistance market include
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